BDBM50240612 CHEMBL306946::GNF-PF-2691::Indolo[2,1-b]quinazoline-6,12-dione::TCMDC-125859::TRYPTANTHRIN::US10669273, Compound 5a

SMILES O=C1c2ccccc2-n2c1nc1ccccc1c2=O

InChI Key InChIKey=VQQVWGVXDIPORV-UHFFFAOYSA-N

Data  3 KI  16 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50240612   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50240612(CHEMBL306946 | GNF-PF-2691 | Indolo[2,1-b]quinazol...)
Affinity DataIC50:  150nMAssay Description:Inhibition of 5-lipooxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50240612(CHEMBL306946 | GNF-PF-2691 | Indolo[2,1-b]quinazol...)
Affinity DataIC50:  64nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed