BDBM50241990 CHEMBL502489::Camboginol::Garcinol::Garcinol, 1

SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6@@H](-[#6][C@@]12[#6]-[#6@@H](-[#6]\[#6]=[#6](\[#6])-[#6])C([#6])([#6])[C@@]([#6]\[#6]=[#6](\[#6])-[#6])([#6](=O)-[#6](-[#6](=O)-c3ccc(-[#8])c(-[#8])c3)-[#6]1=O)[#6]2=O)-[#6](-[#6])=[#6]

InChI Key InChIKey=YESGFVCPMZHDNK-FIXRDIOOSA-N

Data  1 KI  6 IC50  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50241990   

TargetHistone acetyltransferase p300(Homo sapiens (Human))
Jawaharlal Nehru Centre For Advanced Scientific Research

Curated by ChEMBL
LigandPNGBDBM50241990(CHEMBL502489 | Camboginol | Garcinol | Garcinol, 1)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of HAT p300 catalytic domain by equilibrium dialysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Jawaharlal Nehru Centre For Advanced Scientific Research

Curated by ChEMBL
LigandPNGBDBM50241990(CHEMBL502489 | Camboginol | Garcinol | Garcinol, 1)
Affinity DataKd:  1.80E+3nMAssay Description:Binding affinity to HAT p300 catalytic domain by fluorometric titrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Jawaharlal Nehru Centre For Advanced Scientific Research

Curated by ChEMBL
LigandPNGBDBM50241990(CHEMBL502489 | Camboginol | Garcinol | Garcinol, 1)
Affinity DataKd:  6.60E+3nMAssay Description:Binding affinity to HAT p300 catalytic domain by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed