BDBM50242697 CHEMBL4070214::US9932350, 2-7
SMILES N#Cc1ccc2ncnc(N[C@H]3CC[C@@H](CC3)N3CCOCC3)c2c1
InChI Key InChIKey=HVQXFGHHSFTACS-WKILWMFISA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50242697
Affinity DataEC50: 2.30E+3nMAssay Description:Inhibition of specific binding of [3H]DTG to sigma binding site in Guinea pig brain membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human full length GST tagged IRAK4 expressed in baculovirus infected Sf9 cells using RP7030 peptide as substrate after 30 m...More data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of IRAK4 (unknown origin) by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of IRAK4 (unknown origin) in presence of 5 mM ATP by enzymatic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair