BDBM50245040 CHEMBL4090558
SMILES CCOC(=O)CC[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)\C=C\c1ccc(O)c(OC)c1)C(C)C)C(=O)OCC
InChI Key InChIKey=MRZZVWZLVGNCBE-FJQRSJHESA-N
Data 4 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50245040
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University of Ljubljana
Curated by ChEMBL
University of Ljubljana
Curated by ChEMBL
Affinity DataEC50: 46nMAssay Description:Agonist activity at human NOD2 expressed in HEK-Blue cells assessed as induction of NF-kB transcriptional activity after 18 hrs by SEAP reporter gene...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University of Ljubljana
Curated by ChEMBL
University of Ljubljana
Curated by ChEMBL
Affinity DataEC50: 203nMAssay Description:Agonist activity at human human NOD2 expressed in HEK-Blue NOD2 reporter cells by colorimetry based SEAP assayMore data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University of Ljubljana
Curated by ChEMBL
University of Ljubljana
Curated by ChEMBL
Affinity DataEC50: 99nMAssay Description:Agonist activity at NOD2 in HEK-Blue hNOD2 cells assessed as increase in NFkappaB activation incubated for 18 hrs by SEAP-based spectrophotometry ana...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University of Ljubljana
Curated by ChEMBL
University of Ljubljana
Curated by ChEMBL
Affinity DataEC50: 89nMAssay Description:Agonist activity at NOD2 in HEK-Blue hNOD2 cells assessed as increase in NFkappaB transactivation-mediated SEAP activity measured after 18 hrs by spe...More data for this Ligand-Target Pair