BDBM50246759 CHEMBL4098772

SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCOc2cc3nccc(Nc4ccc5scnc5c4)c3cc2S(=O)(=O)C(C)(C)C)C(C)(C)C)cc1

InChI Key InChIKey=RIEGJNXDHULIKM-GPPJZCFZSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50246759   

Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Shaoxing University

Curated by ChEMBL
LigandPNGBDBM50246759(CHEMBL4098772)
Affinity DataIC50:  656nMAssay Description:Binding affinity to VHL in human THP-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Shaoxing University

Curated by ChEMBL
LigandPNGBDBM50246759(CHEMBL4098772)
Affinity DataKd:  500nMAssay Description:Binding affinity to VHL (unknown origin) assessed as reduction of HIF1alpha derived peptide binding to VHL complex by competitive binding fluorescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed