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Found 2 Enz. Inhib. hit(s) with Target = 'von Hippel-Lindau disease tumor suppressor' and Ligand = 'BDBM50246759'
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Shaoxing University

Curated by ChEMBL
LigandPNGBDBM50246759(CHEMBL4098772)
Affinity DataIC50:  656nMAssay Description:Binding affinity to VHL in human THP-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Shaoxing University

Curated by ChEMBL
LigandPNGBDBM50246759(CHEMBL4098772)
Affinity DataKd:  500nMAssay Description:Binding affinity to VHL (unknown origin) assessed as reduction of HIF1alpha derived peptide binding to VHL complex by competitive binding fluorescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed