BDBM50257807 CHEMBL4073638
SMILES CCOC(=O)N1CCC(CC1)NC(=O)c1ccc2nc(CC)c(N(C)c3nc(cs3)-c3ccc(Cl)cc3)n2c1
InChI Key InChIKey=IJBGDWHAQJDQDM-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50257807
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of glycosylated human ATX using FS-3 as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by fluore...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 6.56E+3nMAssay Description:Inhibition of glycosylated human ATX using FS-3 as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by fluore...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of ATX in rat plasma assessed as reduction in plasma lysophosphatidic acid 18:2 levels after 2 hrs by LC-MS/MS methodMore data for this Ligand-Target Pair