BDBM50264884 3-(2-chlorophenyl)-5-(5-methyl-1-(piperidin-4-yl)-1H-pyrazol-4-yl)isoxazole::CHEMBL504947

SMILES Cc1c(cnn1C1CCNCC1)-c1cc(no1)-c1ccccc1Cl

InChI Key InChIKey=QRRFQNFXXUZNAT-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50264884   

TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50264884(3-(2-chlorophenyl)-5-(5-methyl-1-(piperidin-4-yl)-...)
Affinity DataEC50: >1.00E+5nMAssay Description:Activation of human alpha7 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50264884(3-(2-chlorophenyl)-5-(5-methyl-1-(piperidin-4-yl)-...)
Affinity DataEC50:  18nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50264884(3-(2-chlorophenyl)-5-(5-methyl-1-(piperidin-4-yl)-...)
Affinity DataEC50:  20nMAssay Description:Activation of rat alpha4beta2 nAChR by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed