BDBM50264884 3-(2-chlorophenyl)-5-(5-methyl-1-(piperidin-4-yl)-1H-pyrazol-4-yl)isoxazole::CHEMBL504947
SMILES Cc1c(cnn1C1CCNCC1)-c1cc(no1)-c1ccccc1Cl
InChI Key InChIKey=QRRFQNFXXUZNAT-UHFFFAOYSA-N
Data 3 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50264884
Affinity DataEC50: >1.00E+5nMAssay Description:Activation of human alpha7 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
Affinity DataEC50: 18nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataEC50: 20nMAssay Description:Activation of rat alpha4beta2 nAChR by fluorescence assayMore data for this Ligand-Target Pair