BDBM50278208 CHEMBL4166987

SMILES C[C@@H](C(=O)Nc1ccc(cc1)C(=O)Nc1ccc(F)cc1N)c1ccccc1

InChI Key InChIKey=SCZTZKHHRWDIJY-CQSZACIVSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50278208   

TargetHistone deacetylase 1(Homo sapiens (Human))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50278208(CHEMBL4166987)
Affinity DataIC50:  1.80E+3nMAssay Description:In vitro Thromboxane A2 (TXA2) receptor antagonism was tested by its ability to inhibit the contraction of rat aorta induced by the stable thromboxan...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278208(CHEMBL4166987)
Affinity DataIC50:  579nMAssay Description:Inhibition of full length human C-terminal His-tagged HDAC3/N-terminal GST-tagged NCOR2 (395 to 489 residues) co-expressed in baculovirus infected sf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278208(CHEMBL4166987)
Affinity DataIC50:  210nMAssay Description:Inhibition of human HDAC3/NCOR2 using p53 (379 to 382 residues) derived fluorogenic peptide RHKKAcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50278208(CHEMBL4166987)
Affinity DataIC50:  2.80E+3nMAssay Description:H3 -antagonist potency determined in electrically stimulated guinea-pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed