BDBM50278208 CHEMBL4166987
SMILES C[C@@H](C(=O)Nc1ccc(cc1)C(=O)Nc1ccc(F)cc1N)c1ccccc1
InChI Key InChIKey=SCZTZKHHRWDIJY-CQSZACIVSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50278208
Affinity DataIC50: 1.80E+3nMAssay Description:In vitro Thromboxane A2 (TXA2) receptor antagonism was tested by its ability to inhibit the contraction of rat aorta induced by the stable thromboxan...More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Jadavpur University
Curated by ChEMBL
Jadavpur University
Curated by ChEMBL
Affinity DataIC50: 579nMAssay Description:Inhibition of full length human C-terminal His-tagged HDAC3/N-terminal GST-tagged NCOR2 (395 to 489 residues) co-expressed in baculovirus infected sf...More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Jadavpur University
Curated by ChEMBL
Jadavpur University
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of human HDAC3/NCOR2 using p53 (379 to 382 residues) derived fluorogenic peptide RHKKAcMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:H3 -antagonist potency determined in electrically stimulated guinea-pig ileumMore data for this Ligand-Target Pair