BDBM50281388 CHEMBL4173258

SMILES CN(CC#C)Cc1cc2cc(OCCCN3CCCCC3)ccc2n1C

InChI Key InChIKey=NQDGCGNKNJWZHP-UHFFFAOYSA-N

Data  7 KI  18 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50281388   

TargetHistamine H3 receptor(Homo sapiens (Human))
Iqog, Csic

Curated by ChEMBL
LigandPNGBDBM50281388(CHEMBL4173258)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human H3R expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVesicular acetylcholine transporter(Rattus norvegicus)
Iqog, Csic

Curated by ChEMBL
LigandPNGBDBM50281388(CHEMBL4173258)
Affinity DataKi:  46nMAssay Description:Displacement of (-)-[3H]vesamicol from rat VAChT expressed in rat PC12 cell membranes after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Iqog, Csic

Curated by ChEMBL
LigandPNGBDBM50281388(CHEMBL4173258)
Affinity DataKi:  65nMAssay Description:Displacement of (+)-[3H]pentazocine from human sigma1 receptor expressed in HEK293 cell membranes after 60 mins by liquid scintillation counting meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Iqog, Csic

Curated by ChEMBL
LigandPNGBDBM50281388(CHEMBL4173258)
Affinity DataKi:  326nMAssay Description:Displacement of [3H]DTG from sigma2 receptor in rat liver membranes after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Iqog, Csic

Curated by ChEMBL
LigandPNGBDBM50281388(CHEMBL4173258)
Affinity DataIC50:  78nMAssay Description:Inhibition of recombinant human MAO-B using tyramine as substrate ampliflu red dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Iqog, Csic

Curated by ChEMBL
LigandPNGBDBM50281388(CHEMBL4173258)
Affinity DataIC50:  1.69E+3nMAssay Description:Inhibition of human plasma BuChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Iqog, Csic

Curated by ChEMBL
LigandPNGBDBM50281388(CHEMBL4173258)
Affinity DataIC50:  530nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Iqog, Csic

Curated by ChEMBL
LigandPNGBDBM50281388(CHEMBL4173258)
Affinity DataIC50:  145nMAssay Description:Inhibition of recombinant human MAO-A using tyramine as substrate ampliflu red dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed