BDBM50281388 CHEMBL4173258

SMILES CN(CC#C)Cc1cc2cc(OCCCN3CCCCC3)ccc2n1C

InChI Key InChIKey=NQDGCGNKNJWZHP-UHFFFAOYSA-N

Data  7 KI  18 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50281388   

TargetHistamine H3 receptor(Homo sapiens (Human))
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50281388(CHEMBL4173258)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human H3R expressed in HEK293 cell membranes incubated for 90 mins by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50281388(CHEMBL4173258)
Affinity DataIC50:  1.85E+3nMAssay Description:Inhibition of recombinant human MAOA expressed in baculovirus infected BTI insect cells using p-tyramine as substrate by Amplex red reagent/horseradi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50281388(CHEMBL4173258)
Affinity DataIC50:  145nMAssay Description:Inhibition of recombinant human MAOA expressed in baculovirus infected BTI insect cells using p-tyramine as substrate preincubated for 30 mins follow...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50281388(CHEMBL4173258)
Affinity DataIC50:  1.69E+3nMAssay Description:Inhibition of human plasma butyrylcholinesterase by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50281388(CHEMBL4173258)
Affinity DataIC50:  78nMAssay Description:Inhibition of recombinant human MAOB expressed in baculovirus infected BTI insect cells using p-tyramine as substrate preincubated for 30 mins follow...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50281388(CHEMBL4173258)
Affinity DataIC50:  1.94E+3nMAssay Description:Inhibition of recombinant human MAOB expressed in baculovirus infected BTI insect cells using p-tyramine as substrate by Amplex red reagent/horseradi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50281388(CHEMBL4173258)
Affinity DataIC50:  530nMAssay Description:Inhibition of human acetylcholinesterase expressed in HEK 293 cells using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed