BDBM50283491 CHEMBL1585091

SMILES COC(=O)c1ccc(cc1)-n1c(C)cc(C(=O)CSc2ccc(NC(C)=O)cc2)c1C

InChI Key InChIKey=BCNKQXDDMIBITO-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50283491   

TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283491(CHEMBL1585091)
Affinity DataEC50:  1.50E+3nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283491(CHEMBL1585091)
Affinity DataEC50:  900nMAssay Description:Positive allosteric modulation of rat mGlu8 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))TBA
LigandPNGBDBM50283491(CHEMBL1585091)
Affinity DataEC50:  900nMAssay Description:Positive allosteric modulation of mGluR8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))TBA
LigandPNGBDBM50283491(CHEMBL1585091)
Affinity DataEC50:  3.20E+3nMAssay Description:Positive allosteric modulation of mGluR4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM50283491(CHEMBL1585091)
Affinity DataEC50:  1.50E+3nMAssay Description:Positive allosteric modulation of mGluR7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))TBA
LigandPNGBDBM50283491(CHEMBL1585091)
Affinity DataEC50:  3.20E+3nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in glutamate-induced calcium mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed