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Found 2 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 8' and Ligand = 'BDBM50283491'
TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))TBA
LigandPNGBDBM50283491(CHEMBL1585091)
Affinity DataEC50:  900nMAssay Description:Positive allosteric modulation of mGluR8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283491(CHEMBL1585091)
Affinity DataEC50:  900nMAssay Description:Positive allosteric modulation of rat mGlu8 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed