BDBM50346953 CHEMBL1795713::CHEMBL1795716

SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)CC[C@H]4NC(=O)c1cccc(I)c1)ccc5O

InChI Key InChIKey=UKTOBZMVJHBRHZ-RMTHQLOBSA-N

Data  6 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50346953   

TargetMu-type opioid receptor(MOUSE)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346953(CHEMBL1795713 | CHEMBL1795716)
Affinity DataKi:  0.970nMAssay Description:Displacement of [125I]-BNtxA from mouse cloned MOR-1 expressed in CHO cell membrane after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346953(CHEMBL1795713 | CHEMBL1795716)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]-DAMGO from MOR-1 expressed in CHO cells after 150 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346953(CHEMBL1795713 | CHEMBL1795716)
Affinity DataKi:  2.45nMAssay Description:Displacement of [125I]-BNtxA from mouse cloned DOR-1 expressed in CHO cell membrane after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346953(CHEMBL1795713 | CHEMBL1795716)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]-U69593 from KOR-1 expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346953(CHEMBL1795713 | CHEMBL1795716)
Affinity DataKi:  47.2nMAssay Description:Displacement of [125I]-BNtxA from mouse cloned KOR-1 expressed in CHO cell membrane after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346953(CHEMBL1795713 | CHEMBL1795716)
Affinity DataKi:  71nMAssay Description:Displacement of [3H]-DPDPE from DOR-1 expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346953(CHEMBL1795713 | CHEMBL1795716)
Affinity DataKd:  0.0800nMAssay Description:Binding affinity to MOR-1 expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed