BDBM50355480 CHEMBL1835747

SMILES Nc1nc(Nc2ccc(cc2)N2CCOCC2)nn1-c1ccccn1

InChI Key InChIKey=OOBFAKQHFQIPMU-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50355480   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50355480(CHEMBL1835747)
Affinity DataKi:  5nMAssay Description:Displacement of [33P]ATP from human recombinant FLT3 domain after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50355480(CHEMBL1835747)
Affinity DataKi:  18nMAssay Description:Displacement of [33P]ATP from human recombinant c-KIT domain after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50355480(CHEMBL1835747)
Affinity DataIC50:  18nMAssay Description:Inhibition of human recombinant c-Kit by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50355480(CHEMBL1835747)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant FLT3 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed