BDBM50382934 CHEMBL2029567
SMILES O[C@]1(CC[C@@H](CC1)N[C@H]1CCN(C1)C(=O)C1CCN(CC1)c1cccc(n1)C(F)(F)F)c1ccc(cn1)-c1ncccn1
InChI Key InChIKey=ZJHJRHOLIVTDGJ-JYUFKMNQSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50382934
Affinity DataIC50: 8.80nMAssay Description:Antagonist activity at CCR2 receptor in human PBMC assessed as inhibition of MCP1-mediated leukocyte chemotaxis after 30 mins by microscopyMore data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Displacement of [125I]MCP1 from human CCR2 in PBMC after 30 mins by gamma countingMore data for this Ligand-Target Pair
Affinity DataIC50: 88nMAssay Description:Antagonist activity at CCR2 receptor in human whole blood assessed as inhibition of alexa-tagged MCP-induced effect 30 mins by flow cytometryMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair