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Found 3 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 2' and Ligand = 'BDBM50382934'
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382934(CHEMBL2029567)
Affinity DataIC50:  4.5nMAssay Description:Displacement of [125I]MCP1 from human CCR2 in PBMC after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382934(CHEMBL2029567)
Affinity DataIC50:  8.80nMAssay Description:Antagonist activity at CCR2 receptor in human PBMC assessed as inhibition of MCP1-mediated leukocyte chemotaxis after 30 mins by microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382934(CHEMBL2029567)
Affinity DataIC50:  88nMAssay Description:Antagonist activity at CCR2 receptor in human whole blood assessed as inhibition of alexa-tagged MCP-induced effect 30 mins by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed