BDBM50386408 CHEMBL2047297
SMILES CCCCNc1cccc(NC(=O)c2ccccc2Br)c1
InChI Key InChIKey=GSHBQNVGNFDHND-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50386408
Affinity DataIC50: 340nMAssay Description:Inhibition of SFLLRN-NH2-stimulated PAR1-mediated platelet activation in platelet-rich human plasma assessed as surface expression of P-selectin afte...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Negative allosteric modulation of PAR1 in human EAhy926 cells assessed as reduction in TFLLRN-NH2-induced intracellular calcium mobilization incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 970nMAssay Description:Antagonist activity at PAR1 in human EAhy926 cells assessed as inhibition of TFLLRN-NH2-induced intracellular calcium mobilization pretreated for 15 ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at PAR1 in human EAhy926 cells assessed as inhibition of TFLLRN-NH2-induced intracellular calcium mobilization pretreated for 15 ...More data for this Ligand-Target Pair