BDBM50436285 CHEMBL2398743::US8633226, 466

SMILES CC(C)CC(=O)N[C@H](C(C)C)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1

InChI Key InChIKey=RSEPHLOGMONLPT-OFNKIYASSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50436285   

TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50436285(CHEMBL2398743 | US8633226, 466)
Affinity DataKi:  2.60nM ΔG°:  -11.7kcal/moleT: 2°CAssay Description:For radioligand competition studies, a final concentration of 1x105 THP-1 monocytic leukemia cells are combined with 100 μg of LS WGA PS beads (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50436285(CHEMBL2398743 | US8633226, 466)
Affinity DataIC50:  2.90nMAssay Description:Binding affinity to human CCR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50436285(CHEMBL2398743 | US8633226, 466)
Affinity DataIC50:  1.90nMAssay Description:Antagonist activity at human CCR1 assessed as inhibition of MIP1alpha-induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed