Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 1' and Ligand = 'BDBM50436285'
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50436285(CHEMBL2398743 | US8633226, 466)
Affinity DataKi:  2.60nM ΔG°:  -49.0kJ/moleT: 2°CAssay Description:For radioligand competition studies, a final concentration of 1x105 THP-1 monocytic leukemia cells are combined with 100 μg of LS WGA PS beads (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50436285(CHEMBL2398743 | US8633226, 466)
Affinity DataIC50:  1.90nMAssay Description:Antagonist activity at human CCR1 assessed as inhibition of MIP1alpha-induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50436285(CHEMBL2398743 | US8633226, 466)
Affinity DataIC50:  2.90nMAssay Description:Binding affinity to human CCR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed