BDBM50436963 CHEMBL2402255

SMILES CCOC(=O)c1cc(C#N)c(nc1C)N1CC(C1)NC(=O)NS(=O)(=O)c1ccc(Cl)s1

InChI Key InChIKey=DXRGSOKOVRDWNW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50436963   

TargetP2Y purinoceptor 12(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50436963(CHEMBL2402255)
Affinity DataIC50:  25nMAssay Description:Antagonist activity at P2Y12 receptor (unknown origin) assessed as inhibition of GTPgammaS binding after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50436963(CHEMBL2402255)
Affinity DataIC50:  6nMAssay Description:Inhibition of human P2Y12More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50436963(CHEMBL2402255)
Affinity DataIC50:  9.5nMAssay Description:Antagonist activity at P2Y12 receptor in human washed platelets assessed as inhibition of fibrinogen-induced aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50436963(CHEMBL2402255)
Affinity DataIC50:  6.30nMAssay Description:Displacement of [125I]-AZ11931285 from P2Y12 receptor (unknown origin) after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed