Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'P2Y purinoceptor 12' and Ligand = 'BDBM50436963'
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50436963(CHEMBL2402255)
Affinity DataIC50:  6nMAssay Description:Inhibition of human P2Y12More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50436963(CHEMBL2402255)
Affinity DataIC50:  6.30nMAssay Description:Displacement of [125I]-AZ11931285 from P2Y12 receptor (unknown origin) after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50436963(CHEMBL2402255)
Affinity DataIC50:  9.5nMAssay Description:Antagonist activity at P2Y12 receptor in human washed platelets assessed as inhibition of fibrinogen-induced aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50436963(CHEMBL2402255)
Affinity DataIC50:  25nMAssay Description:Antagonist activity at P2Y12 receptor (unknown origin) assessed as inhibition of GTPgammaS binding after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed