BDBM50442995 CHEMBL3086870
SMILES Fc1ccc2nc3C(=O)c4ccccc4-n3c(=O)c2c1
InChI Key InChIKey=DRHLXNRAFXVHOY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50442995
Affinity DataKi: 876nMAssay Description:Mixed type uncompetitive inhibition of recombinant full length C-terminal His-tagged human TDO expressed in Escherichia coli using L-Trp as substrate...More data for this Ligand-Target Pair
Affinity DataKi: 1.05E+5nMAssay Description:Uncompetitive inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) in presence of va...More data for this Ligand-Target Pair
Affinity DataIC50: 241nMAssay Description:Inhibition of TDO (unknown origin) expressed in HEK293 cells using L-Trp as substrate after 8 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 503nMAssay Description:Inhibition of TDO in human U87 MG cells using L-Trp as substrate after 8 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 9.81E+3nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged human TDO expressed in Escherichia coli using L-Trp as substrate after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.68E+4nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) assessed as reduction in L-kynu...More data for this Ligand-Target Pair
Affinity DataIC50: 3.78E+4nMAssay Description:Inhibition of recombinant human IDO2 expressed in human U87MG cells assessed as reduction in kynurenine formation using L-tryptophan as substrate aft...More data for this Ligand-Target Pair
Affinity DataIC50: 8.64E+5nMAssay Description:Competitive inhibition of human recombinant IDO1 using L-tryptophan as substrateMore data for this Ligand-Target Pair