BDBM50446376 CHEMBL3109630

SMILES COc1cc2c(cc1OCCCN1CCCC1)N=C(N)C21CCC1

InChI Key InChIKey=BKCDJTRMYWSXMC-UHFFFAOYSA-N

Data  17 IC50  3 Kd

PDB links: 2 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50446376   

TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
Mercachem

Curated by ChEMBL

LigandBDBM50446376(CHEMBL3109630)Copy SMILESCopy InChI

Affinity DataIC50:  11nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT1 (794 to 1294 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLMCE
PC cidPC sidPDBSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Mercachem

Curated by ChEMBL

LigandBDBM50446376(CHEMBL3109630)Copy SMILESCopy InChI

Affinity DataIC50:  13nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT2 (785 to 1210 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMCE
PC cidPC sidPDBSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI