BDBM50453751 CHEMBL4210534

SMILES C1COCCNCc2ccc3ccc(CNCCOCCNCc4ccc5ccc(CN1)cc5c4)cc3c2

InChI Key InChIKey=GAVOKMJEFXZQJQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50453751   

TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
Russian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50453751(CHEMBL4210534)
Affinity DataIC50:  55nMAssay Description:Inhibition of human APE1 assessed as reduction in abasic sites DNA cleavage using 6-FAM/TAMRA labelled 17-Tphi as substrate by fluorescence-based ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed