BDBM50459189 CHEMBL4211248

SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CNC(=O)C[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCC(O)=O)NC(C)=O)C(=O)NCC(=O)N2CCC[C@@H]2C(=O)N2CCC[C@H]2C(=O)N[C@@H](CCC(O)=O)C(=O)N1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CS)C(=O)NCC(N)=O

InChI Key InChIKey=POLJNYIJVUVTCT-NPTFYBNASA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50459189   

TargetInsulin-degrading enzyme(Mus musculus (Mouse))
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459189(CHEMBL4211248)
Affinity DataIC50:  22nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459189(CHEMBL4211248)
Affinity DataKd:  22nMAssay Description:Binding affinity to IDE E111Q mutant (unknown origin) using N-terminal FITC-labeled compound after 2 hrs in absence of light at 298 K by fluorescence...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed