BDBM50459189 CHEMBL4211248
SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CNC(=O)C[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCC(O)=O)NC(C)=O)C(=O)NCC(=O)N2CCC[C@@H]2C(=O)N2CCC[C@H]2C(=O)N[C@@H](CCC(O)=O)C(=O)N1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CS)C(=O)NCC(N)=O
InChI Key InChIKey=POLJNYIJVUVTCT-NPTFYBNASA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50459189
TargetInsulin-degrading enzyme(Mus musculus (Mouse))
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataKd: 22nMAssay Description:Binding affinity to IDE E111Q mutant (unknown origin) using N-terminal FITC-labeled compound after 2 hrs in absence of light at 298 K by fluorescence...More data for this Ligand-Target Pair