Found 2 Enz. Inhib. hit(s) with Target = 'Insulin-degrading enzyme' and Ligand = 'BDBM50459189' TargetInsulin-degrading enzyme(Mus musculus (Mouse))
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Peking University Shenzhen Graduate School
Curated by ChEMBL
Peking University Shenzhen Graduate School
Curated by ChEMBL
Affinity DataKd: 22nMAssay Description:Binding affinity to IDE E111Q mutant (unknown origin) using N-terminal FITC-labeled compound after 2 hrs in absence of light at 298 K by fluorescence...More data for this Ligand-Target Pair
