BDBM50503421 CHEMBL4587325
SMILES C\C(=C\C#N)c1ccc(Cl)cc1Cl
InChI Key InChIKey=UNHBZLNCSUCMET-DAXSKMNVSA-N
Data 6 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50503421
TargetGABA A receptor alpha-1/beta-1/gamma-2(Homo sapiens (Human))
University Of Vienna
Curated by ChEMBL
University Of Vienna
Curated by ChEMBL
Affinity DataEC50: 1.00E+4nMAssay Description:Positive allosteric modulation of GABA-A alpha1beta1(S290N)gamma2S mutant receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as i...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
University Of Vienna
Curated by ChEMBL
University Of Vienna
Curated by ChEMBL
Affinity DataEC50: 1.03E+5nMAssay Description:Positive allosteric modulation of GABA-A alpha1beta3(N265S)gamma2S mutant receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as i...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
University Of Vienna
Curated by ChEMBL
University Of Vienna
Curated by ChEMBL
Affinity DataEC50: 1.71E+5nMAssay Description:Positive allosteric modulation of GABA-A alpha1beta3(F289S)gamma2S mutant receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as i...More data for this Ligand-Target Pair
TargetGABA A receptor alpha-1/beta-1/gamma-2(Homo sapiens (Human))
University Of Vienna
Curated by ChEMBL
University Of Vienna
Curated by ChEMBL
Affinity DataEC50: 1.48E+5nMAssay Description:Positive allosteric modulation of GABA-A alpha1beta1gamma2S receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as increase in GAB...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
University Of Vienna
Curated by ChEMBL
University Of Vienna
Curated by ChEMBL
Affinity DataEC50: 1.50E+4nMAssay Description:Positive allosteric modulation of GABA-A alpha1beta2gamma2S receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as increase in GAB...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
University Of Vienna
Curated by ChEMBL
University Of Vienna
Curated by ChEMBL
Affinity DataEC50: 1.30E+4nMAssay Description:Positive allosteric modulation of GABA-A alpha1beta3gamma2S receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as increase in GAB...More data for this Ligand-Target Pair