BDBM50511478 CHEMBL4519003
SMILES CCc1ccc(cc1-c1cc(C)cc(c1)-c1cnc2cnccn12)C(=O)Nc1cc(F)cc(c1)C(F)(F)F
InChI Key InChIKey=SERAEYFDVQXTIX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50511478
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Jinan University
Curated by ChEMBL
Jinan University
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged Bcr-Abl expressed in baculovirus expression system using tyrosine-2 peptide as substrate after...More data for this Ligand-Target Pair
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Jinan University
Curated by ChEMBL
Jinan University
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant human GST-tagged DDR1 catalytic domain (440 to 876 residues) expressed in baculovirus expression system using Fluorescein-p...More data for this Ligand-Target Pair
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibition of recombinant human GST-tagged DDR2 cytoplasmic domain (427 to 855 residues) expressed in baculovirus expression system using Fluorescein...More data for this Ligand-Target Pair
Affinity DataKd: 86nMAssay Description:Binding affinity to wild type human partial length DDR2 (V555 to E855 residues) expressed in mammalian expression system after 1 hr by Kinomescan met...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system after 1 hr by Kinomescan meth...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to wild-type human partial length CLK4 (R135 to K481 residues) expressed in bacterial expression system after 1 hr by Kinomescan met...More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Jinan University
Curated by ChEMBL
Jinan University
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant His-tagged c-Kit cytoplasmic domain (544 to 976 residues) expressed in baculovirus expression system using Ser/Thr 6 ...More data for this Ligand-Target Pair
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Jinan University
Curated by ChEMBL
Jinan University
Curated by ChEMBL
Affinity DataKd: 7.80nMAssay Description:Binding affinity to wild type human partial length DDR1 (R565 to V876 residues) expressed in bacterial expression system after 1 hr by Kinomescan met...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type 1D(Homo sapiens (Human))
Jinan University
Curated by ChEMBL
Jinan University
Curated by ChEMBL
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to wild-type human partial length CAMK1D (M1 to K299 residues) expressed in bacterial expression system after 1 hr by Kinomescan met...More data for this Ligand-Target Pair