BDBM50511993 CHEMBL4472879

SMILES O=C(N[C@H]1C[C@@H]1c1ccccc1)[C@@H]1CN(C[C@H]1C(=O)N[C@H]1C[C@@H]1c1ccccc1)C(=O)c1ccc(cc1)C(=O)N1C[C@H]([C@@H](C1)C(=O)N[C@H]1C[C@@H]1c1ccccc1)C(=O)N[C@H]1C[C@@H]1c1ccccc1

InChI Key InChIKey=ABZBNXFGYUSVCJ-UYMKNZQYSA-N

Data  6 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50511993   

TargetToll-like receptor 1(Homo sapiens)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50511993(CHEMBL4472879)
Affinity DataEC50:  0.110nMAssay Description:Agonist activity at TLR1/2 in human THP-1 cells assessed as increase in TNF-alpha release incubated for 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 2(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50511993(CHEMBL4472879)
Affinity DataEC50:  0.110nMAssay Description:Agonist activity at TLR2 in human cells by cell based assayMore data for this Ligand-Target Pair
TargetToll-like receptor 1(Homo sapiens)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50511993(CHEMBL4472879)
Affinity DataEC50:  1.30nMAssay Description:In vitro histamine H3 receptor antagonist activity was determined on guinea pig jejunumMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetToll-like receptor 2(Mus musculus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50511993(CHEMBL4472879)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at TLR1/TLR2 in wild type C57BL/6J mouse macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50511993(CHEMBL4472879)
Affinity DataEC50:  0.110nMAssay Description:Histamine H2-receptor activity on isolated spontaneously beating guinea pig atriumMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50511993(CHEMBL4472879)
Affinity DataEC50:  0.110nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In DepthDetails PubMed