BDBM50514710 CHEMBL4555677

SMILES Brc1ccc2cc(sc2c1)C(=O)Nc1cccc2[nH]ccc12

InChI Key InChIKey=REBSMDZUSJUELV-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50514710   

TargetDeoxyhypusine synthase(Homo sapiens)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514710(CHEMBL4555677)
Affinity DataIC50:  6.90E+3nMAssay Description:Competitive inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction i...More data for this Ligand-Target Pair
TargetDeoxyhypusine synthase(Homo sapiens)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514710(CHEMBL4555677)
Affinity DataIC50:  5.60E+4nMAssay Description:Competitive inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction i...More data for this Ligand-Target Pair
TargetDeoxyhypusine synthase(Homo sapiens)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514710(CHEMBL4555677)
Affinity DataIC50:  5.60E+4nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
TargetDeoxyhypusine synthase(Homo sapiens)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514710(CHEMBL4555677)
Affinity DataIC50:  62nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
TargetDeoxyhypusine synthase(Homo sapiens)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514710(CHEMBL4555677)
Affinity DataIC50:  62nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair