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Found 138 Enz. Inhib. hit(s) with Target = 'Deoxyhypusine synthase'
TargetDeoxyhypusine synthase(Plasmodium falciparum)
Institute For Medical Parasitology

Curated by ChEMBL
LigandPNGBDBM50216786(CHEMBL229457 | N-(7-Amino-heptyl)-guanidine | N-gu...)
Affinity DataKi:  100nMAssay Description:Inhibition of recombinant deoxyhypusine synthase in Plasmodium falciparum NF54More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyhypusine synthase(Plasmodium falciparum)
Institute For Medical Parasitology

Curated by ChEMBL
LigandPNGBDBM50216787(1,7-diaminoheptane | CHEMBL28242 | Heptane-1,7-dia...)
Affinity DataKi:  5.00E+4nMAssay Description:Inhibition of recombinant deoxyhypusine synthase in Plasmodium falciparum NF54More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50612294(CHEMBL5281395)
Affinity DataIC50:  9.20nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand InfoPDB
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50612293(CHEMBL5265996)
Affinity DataIC50:  11nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50612290(CHEMBL5288132)
Affinity DataIC50:  12nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50583904(CHEMBL5091313)
Affinity DataIC50:  14nMAssay Description:Inhibition of DHPS (unknown origin ) incubated for 30 mins by NAD/NADH-Glow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50612285(CHEMBL5269564)
Affinity DataIC50:  14nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand InfoPDB
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50612287(CHEMBL5274333)
Affinity DataIC50:  18nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand InfoPDB
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50612292(CHEMBL5268272)
Affinity DataIC50:  26nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50612295(CHEMBL5267547)
Affinity DataIC50:  29nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetDeoxyhypusine synthase(Rattus norvegicus)
National Institute Of Dental Research

Curated by ChEMBL
LigandPNGBDBM50216786(CHEMBL229457 | N-(7-Amino-heptyl)-guanidine | N-gu...)
Affinity DataIC50:  30nMAssay Description:In vitro IC50 value by measuring the inhibition of deoxyhypusine synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50612291(CHEMBL5278471)
Affinity DataIC50:  30nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50583911(CHEMBL5079375)
Affinity DataIC50:  40nMAssay Description:Inhibition of DHPS (unknown origin ) incubated for 30 mins by NAD/NADH-Glow assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50583914(CHEMBL5074971)
Affinity DataIC50:  50nMAssay Description:Inhibition of DHPS (unknown origin ) incubated for 30 mins by NAD/NADH-Glow assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50514710(CHEMBL4555677)
Affinity DataIC50:  62nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50514710(CHEMBL4555677)
Affinity DataIC50:  62nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50612294(CHEMBL5281395)
Affinity DataIC50:  69nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand InfoPDB
TargetDeoxyhypusine synthase(Rattus norvegicus)
National Institute Of Dental Research

Curated by ChEMBL
LigandPNGBDBM50032510(CHEMBL103941 | N-[7-(7-Guanidino-heptylamino)-hept...)
Affinity DataIC50:  80nMAssay Description:In vitro IC50 value by measuring the inhibition of deoxyhypusine synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50514715(CHEMBL4543218)
Affinity DataIC50:  92nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50583906(CHEMBL5075342)
Affinity DataIC50:  100nMAssay Description:Inhibition of DHPS (unknown origin ) incubated for 30 mins by NAD/NADH-Glow assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50612289(CHEMBL5282634)
Affinity DataIC50:  110nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50514717(CHEMBL4462702)
Affinity DataIC50:  120nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50216786(CHEMBL229457 | N-(7-Amino-heptyl)-guanidine | N-gu...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50612288(CHEMBL5281552)
Affinity DataIC50:  150nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetDeoxyhypusine synthase(Rattus norvegicus)
National Institute Of Dental Research

Curated by ChEMBL
LigandPNGBDBM50032469(CHEMBL103613 | N-[4-(4-Amino-butylamino)-butyl]-gu...)
Affinity DataIC50:  160nMAssay Description:In vitro IC50 value by measuring the inhibition of deoxyhypusine synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50612286(CHEMBL5287156)
Affinity DataIC50:  160nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50612290(CHEMBL5288132)
Affinity DataIC50:  170nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50583898(CHEMBL5084409)
Affinity DataIC50:  180nMAssay Description:Inhibition of DHPS (unknown origin ) incubated for 30 mins by NAD/NADH-Glow assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50583902(CHEMBL5091281)
Affinity DataIC50:  180nMAssay Description:Inhibition of DHPS (unknown origin ) incubated for 30 mins by NAD/NADH-Glow assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50612293(CHEMBL5265996)
Affinity DataIC50:  230nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetDeoxyhypusine synthase(Rattus norvegicus)
National Institute Of Dental Research

Curated by ChEMBL
LigandPNGBDBM50032467(CHEMBL102939 | N-[7-(7-Amino-heptylamino)-heptyl]-...)
Affinity DataIC50:  300nMAssay Description:In vitro IC50 value by measuring the inhibition of deoxyhypusine synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50583900(CHEMBL5090481)
Affinity DataIC50:  320nMAssay Description:Inhibition of DHPS (unknown origin ) incubated for 30 mins by NAD/NADH-Glow assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50583895(CHEMBL5078063)
Affinity DataIC50:  330nMAssay Description:Inhibition of DHPS (unknown origin ) incubated for 30 mins by NAD/NADH-Glow assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50612285(CHEMBL5269564)
Affinity DataIC50:  410nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand InfoPDB
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50514706(CHEMBL4442298)
Affinity DataIC50:  430nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50612284(CHEMBL5283409)
Affinity DataIC50:  440nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50216786(CHEMBL229457 | N-(7-Amino-heptyl)-guanidine | N-gu...)
Affinity DataIC50:  500nMAssay Description:Competitive inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50583915(CHEMBL5091279)
Affinity DataIC50:  530nMAssay Description:Inhibition of DHPS (unknown origin ) incubated for 30 mins by NAD/NADH-Glow assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDeoxyhypusine synthase(Rattus norvegicus)
National Institute Of Dental Research

Curated by ChEMBL
LigandPNGBDBM50032485(CHEMBL101419 | N-(8-Amino-octyl)-guanidine)
Affinity DataIC50:  550nMAssay Description:In vitro IC50 value by measuring the inhibition of deoxyhypusine synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50583889(CHEMBL5070084)
Affinity DataIC50:  560nMAssay Description:Inhibition of DHPS (unknown origin ) incubated for 30 mins by NAD/NADH-Glow assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50612291(CHEMBL5278471)
Affinity DataIC50:  580nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50612295(CHEMBL5267547)
Affinity DataIC50:  630nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50583908(CHEMBL5081296)
Affinity DataIC50:  640nMAssay Description:Inhibition of DHPS (unknown origin ) incubated for 30 mins by NAD/NADH-Glow assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDeoxyhypusine synthase(Rattus norvegicus)
National Institute Of Dental Research

Curated by ChEMBL
LigandPNGBDBM50032495(CHEMBL105951 | N-[3-(3-Amino-propoxy)-propyl]-guan...)
Affinity DataIC50:  700nMAssay Description:In vitro IC50 value by measuring the inhibition of deoxyhypusine synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50612292(CHEMBL5268272)
Affinity DataIC50:  790nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50514699(CHEMBL4447948)
Affinity DataIC50:  840nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50583899(CHEMBL5075319)
Affinity DataIC50:  1.17E+3nMAssay Description:Inhibition of DHPS (unknown origin ) incubated for 30 mins by NAD/NADH-Glow assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDeoxyhypusine synthase(Rattus norvegicus)
National Institute Of Dental Research

Curated by ChEMBL
LigandPNGBDBM50032503(CHEMBL280222 | N-[3-(3-Amino-propylamino)-propyl]-...)
Affinity DataIC50:  1.20E+3nMAssay Description:In vitro IC50 value by measuring the inhibition of deoxyhypusine synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50216786(CHEMBL229457 | N-(7-Amino-heptyl)-guanidine | N-gu...)
Affinity DataIC50:  1.72E+3nMAssay Description:Inhibition of DHPS (unknown origin ) incubated for 30 mins by NAD/NADH-Glow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyhypusine synthase(Rattus norvegicus)
National Institute Of Dental Research

Curated by ChEMBL
LigandPNGBDBM50032472(CHEMBL321347 | N-[3-(3-Amino-propylsulfanyl)-propy...)
Affinity DataIC50:  1.90E+3nMAssay Description:In vitro IC50 value by measuring the inhibition of deoxyhypusine synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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