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Found 5 Enz. Inhib. hit(s) with Target = 'Deoxyhypusine synthase' and Ligand = 'BDBM50216786'
TargetDeoxyhypusine synthase(Plasmodium falciparum)
Institute For Medical Parasitology

Curated by ChEMBL
LigandPNGBDBM50216786(CHEMBL229457 | N-(7-Amino-heptyl)-guanidine | N-gu...)
Affinity DataKi:  100nMAssay Description:Inhibition of recombinant deoxyhypusine synthase in Plasmodium falciparum NF54More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyhypusine synthase(Rattus norvegicus)
National Institute Of Dental Research

Curated by ChEMBL
LigandPNGBDBM50216786(CHEMBL229457 | N-(7-Amino-heptyl)-guanidine | N-gu...)
Affinity DataIC50:  30nMAssay Description:In vitro IC50 value by measuring the inhibition of deoxyhypusine synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetDeoxyhypusine synthase(Homo sapiens)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50216786(CHEMBL229457 | N-(7-Amino-heptyl)-guanidine | N-gu...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyhypusine synthase(Homo sapiens)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50216786(CHEMBL229457 | N-(7-Amino-heptyl)-guanidine | N-gu...)
Affinity DataIC50:  500nMAssay Description:Competitive inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyhypusine synthase(Homo sapiens)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50216786(CHEMBL229457 | N-(7-Amino-heptyl)-guanidine | N-gu...)
Affinity DataIC50:  1.72E+3nMAssay Description:Inhibition of DHPS (unknown origin ) incubated for 30 mins by NAD/NADH-Glow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed