BDBM50521067 CHEMBL4452051

SMILES COc1ccc(cc1)-c1nnc(NC(=O)c2cc(nc3ccccc23)-c2cccs2)o1

InChI Key InChIKey=DXJQMVLYVBDLDV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50521067   

TargetAdenylate cyclase type 8(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50521067(CHEMBL4452051)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of human AC8 expressed in HEK293 cells assessed as decrease in A23187-stimulated cAMP accumulation preincubated for 30 mins followed by A2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50521067(CHEMBL4452051)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of human AC1 expressed in HEK293 cells assessed as decrease in A23187-stimulated cAMP accumulation preincubated for 30 mins followed by A2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed