BDBM50532743 CHEMBL4527749
SMILES CCN1CCC(CCNC(=O)Nc2nc3ccc(Sc4nnc5ccc(nn45)-c4cccs4)cc3s2)CC1
InChI Key InChIKey=TYRAWDXLPFZNOP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50532743
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Sanofi-Aventis Germany
Curated by ChEMBL
Sanofi-Aventis Germany
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of phosphorylated MET in human MKN45 cells assessed as reduction in pMET Y1230/1234/1235 level incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Sanofi-Aventis Germany
Curated by ChEMBL
Sanofi-Aventis Germany
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of wild type phosphorylated MET (unknown origin) pre-incubated for 30 mins before biotinylated poly(glutamate-alanine-tyrosine) peptide ad...More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Sanofi-Aventis Germany
Curated by ChEMBL
Sanofi-Aventis Germany
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of phosphorylated MET in human MKN45 cells assessed as reduction in pMET Y1230/1234/1235 level incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Sanofi-Aventis Germany
Curated by ChEMBL
Sanofi-Aventis Germany
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of phosphorylated MET Y1230H mutant (unknown origin) pre-incubated for 30 mins before biotinylated poly(glutamate-alanine-tyrosine) peptid...More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Sanofi-Aventis Germany
Curated by ChEMBL
Sanofi-Aventis Germany
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of phosphorylated MET Y1230H mutant (unknown origin) pre-incubated for 30 mins before biotinylated poly(glutamate-alanine-tyrosine) peptid...More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Sanofi-Aventis Germany
Curated by ChEMBL
Sanofi-Aventis Germany
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of wild type phosphorylated MET (unknown origin) pre-incubated for 30 mins before biotinylated poly(glutamate-alanine-tyrosine) peptide ad...More data for this Ligand-Target Pair