Found 6 Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50532743' TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Sanofi-Aventis Germany
Curated by ChEMBL
Sanofi-Aventis Germany
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of wild type phosphorylated MET (unknown origin) pre-incubated for 30 mins before biotinylated poly(glutamate-alanine-tyrosine) peptide ad...More data for this Ligand-Target Pair
3D Structure (crystal)TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Sanofi-Aventis Germany
Curated by ChEMBL
Sanofi-Aventis Germany
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of wild type phosphorylated MET (unknown origin) pre-incubated for 30 mins before biotinylated poly(glutamate-alanine-tyrosine) peptide ad...More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Sanofi-Aventis Germany
Curated by ChEMBL
Sanofi-Aventis Germany
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of phosphorylated MET Y1230H mutant (unknown origin) pre-incubated for 30 mins before biotinylated poly(glutamate-alanine-tyrosine) peptid...More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Sanofi-Aventis Germany
Curated by ChEMBL
Sanofi-Aventis Germany
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of phosphorylated MET Y1230H mutant (unknown origin) pre-incubated for 30 mins before biotinylated poly(glutamate-alanine-tyrosine) peptid...More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Sanofi-Aventis Germany
Curated by ChEMBL
Sanofi-Aventis Germany
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of phosphorylated MET in human MKN45 cells assessed as reduction in pMET Y1230/1234/1235 level incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Sanofi-Aventis Germany
Curated by ChEMBL
Sanofi-Aventis Germany
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of phosphorylated MET in human MKN45 cells assessed as reduction in pMET Y1230/1234/1235 level incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
