BDBM50540741 CHEMBL4640019
SMILES OCc1cncc(c1)-c1ccc2[nH]nc(C(=O)NCC3CCOCC3)c2c1
InChI Key InChIKey=HMUYSTSHIXJVRO-UHFFFAOYSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50540741
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged GSK3beta (1 to 420 end residues) expressed in baculovirus expression system using u...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Angelini Pharma
Curated by ChEMBL
Angelini Pharma
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells assessed as reduction in tail current by measuring tail current amplitude measured after deploarizat...More data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of GSK3beta (unknown origin) transfected in HEK cells co-transfected with tau assessed as reduction in tau phosphorylation incubated for 1...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:Inhibition of human recombinant GSK3alpha using Ulight-CFFKNIVTPRTPPPSQGK-amide as substrate incubated for 60 mins in presence of ATP at Km concentra...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of human CDK2/cyclinA using Ulight-CFFKNIVTPRTPPPSQGK-amide as substrate incubated for 30 mins in presence of ATP by LANCE assayMore data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:Inhibition of human LynB using His-tagged Rb truncated protein as substrate incubated for 30 mins in presence of ATP at Km concentration by HTRF assa...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human GRK2 in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human CLK1 in presence of ATPMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Angelini Pharma
Curated by ChEMBL
Angelini Pharma
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:Inhibition of human DYRK1A in presence of ATPMore data for this Ligand-Target Pair