BDBM50549221 CHEMBL4293433
SMILES Oc1cc(Cl)c(I)cc1NCC(=O)N1CCN(CC1)C(=O)C=C
InChI Key InChIKey=JFIFBWVNHLXJFY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50549221
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H358 cells incubated for 6 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 320nMAssay Description:Inhibition of KRas G12C mutant in human NCI-H1792 cells assessed as antiproliferative activity incubated for 3 days by CellTiter-Glo assayMore data for this Ligand-Target Pair