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Found 2 Enz. Inhib. hit(s) with Target = 'GTPase KRas' and Ligand = 'BDBM50549221'
TargetGTPase KRas(Homo sapiens (Human))TBA
LigandPNGBDBM50549221(CHEMBL4293433)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H358 cells incubated for 6 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGTPase KRas(Homo sapiens (Human))TBA
LigandPNGBDBM50549221(CHEMBL4293433)
Affinity DataEC50:  320nMAssay Description:Inhibition of KRas G12C mutant in human NCI-H1792 cells assessed as antiproliferative activity incubated for 3 days by CellTiter-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed