BDBM50561654 CHEMBL4785914
SMILES CNC(=O)c1csc2c(cc(nc12)N1CCC(CC1)OC(=O)N[C@@H](C)COC(F)(F)F)C(F)(F)F
InChI Key InChIKey=UQQUABVWYAPTIQ-JTQLQIEISA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50561654
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of UGT2B17 (unknown origin)More data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of UGT1A1 (unknown origin)More data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Mus musculus)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of mouse UGT8 assessed as redcution in GalCer accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of UGT2B7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of UGT2B15 (unknown origin)More data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Mus musculus)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of mouse UGT8 assessed as redcution in SFT accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of UGT1A6 (unknown origin)More data for this Ligand-Target Pair