BDBM50561654 CHEMBL4785914

SMILES CNC(=O)c1csc2c(cc(nc12)N1CCC(CC1)OC(=O)N[C@@H](C)COC(F)(F)F)C(F)(F)F

InChI Key InChIKey=UQQUABVWYAPTIQ-JTQLQIEISA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50561654   

TargetUDP-glucuronosyltransferase 2B17(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50561654(CHEMBL4785914)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of UGT2B17 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50561654(CHEMBL4785914)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50561654(CHEMBL4785914)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50561654(CHEMBL4785914)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of UGT1A1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Mus musculus)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50561654(CHEMBL4785914)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of mouse UGT8 assessed as redcution in GalCer accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 2B7(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50561654(CHEMBL4785914)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of UGT2B7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 2B15(Homo sapiens)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50561654(CHEMBL4785914)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of UGT2B15 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Mus musculus)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50561654(CHEMBL4785914)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of mouse UGT8 assessed as redcution in SFT accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1-6(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50561654(CHEMBL4785914)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of UGT1A6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed