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Found 4 Enz. Inhib. hit(s) with Target = '2-hydroxyacylsphingosine 1-beta-galactosyltransferase' and Ligand = 'BDBM50561654'
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50561654(CHEMBL4785914)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Mus musculus)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50561654(CHEMBL4785914)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of mouse UGT8 assessed as redcution in GalCer accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50561654(CHEMBL4785914)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Mus musculus)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50561654(CHEMBL4785914)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of mouse UGT8 assessed as redcution in SFT accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed