BDBM50577040 CHEMBL4871361

SMILES CC(C)n1cc(C(=O)Nc2cc(F)c(cc2F)-c2c[nH]c3ncnc(N)c23)c(=O)c(c1)-c1ccc(F)cc1

InChI Key InChIKey=NHYCOOHRGHVZOI-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50577040   

TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
University Of Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50577040(CHEMBL4871361)
Affinity DataIC50: <0.200nMAssay Description:Inhibition of AXL (unknown origin) by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
University Of Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50577040(CHEMBL4871361)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of c-MET (unknown origin) by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
University Of Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50577040(CHEMBL4871361)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of VEGFR1 (unknown origin) by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50577040(CHEMBL4871361)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of VEGFR2 (unknown origin) by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
University Of Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50577040(CHEMBL4871361)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of PDGFRalpha (unknown origin) by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
University Of Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50577040(CHEMBL4871361)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of PDGFRbeta (unknown origin) by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University Of Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50577040(CHEMBL4871361)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of IGF1R (unknown origin) by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50577040(CHEMBL4871361)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of FLT-3 (unknown origin) by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50577040(CHEMBL4871361)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of EGFR (unknown origin) by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University Of Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50577040(CHEMBL4871361)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of ERBB2 (unknown origin) by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
University Of Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50577040(CHEMBL4871361)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of ERBB4 (unknown origin) by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50577040(CHEMBL4871361)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of SRC (unknown origin) by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
University Of Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50577040(CHEMBL4871361)
Affinity DataIC50: >500nMAssay Description:Inhibition of EPHA2 (unknown origin) by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University Of Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50577040(CHEMBL4871361)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of Kit(unknown origin) by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed