BDBM50579346 CHEMBL4867565
SMILES Fc1cccc(c1)S(=O)(=O)n1ccc2c(nc3ccccc3c12)N1CCNCC1
InChI Key InChIKey=QNKGTIWNFNPEJL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 26 hits for monomerid = 50579346
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 0.930nMAssay Description:Binding affinity to 5HT3 receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Displacement of [3H]-LSD from human 5HT6 receptor expressed in HEK293 cell membranes measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 110nMAssay Description:Binding affinity to human adrenergic alpha 2A receptorMore data for this Ligand-Target Pair
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 170nMAssay Description:Binding affinity to human adrenergic beta1 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 170nMAssay Description:Binding affinity to human 5-HT2B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 210nMAssay Description:Binding affinity to human dopamine D3 receptorMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 220nMAssay Description:Binding affinity to human histamine H1 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 437nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cell membranes measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 830nMAssay Description:Binding affinity to human 5-HT2C receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 890nMAssay Description:Binding affinity to human 5-HT1B receptorMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 940nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 1.09E+3nMAssay Description:Binding affinity to human DATMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 1.24E+3nMAssay Description:Binding affinity to human NETMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 1.94E+3nMAssay Description:Binding affinity to human M1 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 5A(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 2.87E+3nMAssay Description:Binding affinity to human 5-HT5A receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 2.88E+3nMAssay Description:Binding affinity to human mu opioid receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 3.00E+3nMAssay Description:Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cell membranes measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 3.01E+3nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A receptor expressed in CHO-K1 cell membranes measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 3.27E+3nMAssay Description:Binding affinity to human kappa opioid receptorMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 3.50E+3nMAssay Description:Binding affinity to human sigma 1 receptorMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 4.39E+3nMAssay Description:Displacement of [3H]-haloperidol from human D2L receptor expressed in HEK293 cell membranes measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 4.61E+3nMAssay Description:Binding affinity to human adrenergic alpha2B receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataIC50: 68nMAssay Description:Antagonist activity at human 5-HT3 receptor expressed in CHO-K1 cells assessed as inhibition of 5-HT induced inward currents preincubated for 30 sec ...More data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair