BDBM50579633 CHEMBL4854225

SMILES COc1ncc-2cc1NS(=O)(=O)c1ccc(Cl)c(c1)C(=O)NCc1ccc(s1)-c1ncnc3cc-2sc13

InChI Key InChIKey=AZBLJXRSEYELKU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50579633   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50579633(CHEMBL4854225)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50579633(CHEMBL4854225)
Affinity DataIC50:  11nMAssay Description:Inhibition of human PIM1 using ARKRRRHPSGPPTA as substrate measured after 1.5 hrs by ADP hunter plus assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50579633(CHEMBL4854225)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mTOR (unknown origin) by LanthaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed