BDBM50590390 CHEMBL5174318

SMILES Cn1cc(cn1)-c1cc(Cl)c(Cl)c2[nH]c3CCN(Cc3c12)C(=O)CO

InChI Key InChIKey=CUFQQVSCNCLUFL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50590390   

TargetCyclic GMP-AMP synthase(Homo sapiens)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50590390(CHEMBL5174318)
Affinity DataIC50:  14nMAssay Description:Inhibition of human cGASMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclic GMP-AMP synthase(Homo sapiens)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50590390(CHEMBL5174318)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of cGAS in human THP-1 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50590390(CHEMBL5174318)
Affinity DataIC50:  442nMAssay Description:Inhibition of mouse cGASMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed