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Found 3 Enz. Inhib. hit(s) with Target = 'Cyclic GMP-AMP synthase' and Ligand = 'BDBM50590390'
TargetCyclic GMP-AMP synthase(Homo sapiens)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50590390(CHEMBL5174318)
Affinity DataIC50:  14nMAssay Description:Inhibition of human cGASMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50590390(CHEMBL5174318)
Affinity DataIC50:  442nMAssay Description:Inhibition of mouse cGASMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclic GMP-AMP synthase(Homo sapiens)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50590390(CHEMBL5174318)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of cGAS in human THP-1 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed