BDBM50598931 CHEMBL5209359

SMILES CCN(CC)c1ccc2c(COC(=O)n3cc(CCNC(C)=O)c4cc(OC)ccc34)cc(=O)oc2c1

InChI Key InChIKey=VVBRRWCZJGFFJC-UHFFFAOYSA-N

Data  4 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50598931   

TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50598931(CHEMBL5209359)
Affinity DataKi:  1.80nMAssay Description:Displacement of 2-[125I]iodomelatonin from human melatonin MT1 receptor stably expressing in human HEK293 cell membranes in presence of light-activat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50598931(CHEMBL5209359)
Affinity DataKi:  2.20nMAssay Description:Displacement of 2-[125I]iodomelatonin from human melatonin MT2 receptor stably expressing in human HEK293 cell membranes in presence of light-activat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50598931(CHEMBL5209359)
Affinity DataKi:  4.60nMAssay Description:Displacement of 2-[125I]iodomelatonin from human melatonin MT2 receptor stably expressing in human HEK293 cell membranes under dark condition by radi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50598931(CHEMBL5209359)
Affinity DataKi:  35nMAssay Description:Displacement of 2-[125I]iodomelatonin from human melatonin MT1 receptor stably expressing in human HEK293 cell membranes under dark condition by radi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50598931(CHEMBL5209359)
Affinity DataEC50:  0.646nMAssay Description:Agonist activity at human melatonin MT2 receptor stably expressing in human HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumula...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50598931(CHEMBL5209359)
Affinity DataEC50:  0.589nMAssay Description:Agonist activity at human melatonin MT1 receptor stably expressing in human HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumula...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50598931(CHEMBL5209359)
Affinity DataEC50:  0.447nMAssay Description:Agonist activity at human melatonin MT1 receptor stably expressing in human HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumula...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50598931(CHEMBL5209359)
Affinity DataEC50:  34nMAssay Description:Agonist activity at human melatonin MT2 receptor stably expressing in human HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumula...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed