BDBM50600748 CHEMBL5176737
SMILES Nc1nc(cn2c1nc1ccccc21)C(=O)NCc1ccccn1
InChI Key InChIKey=QHIATACMHNLOEM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50600748
Affinity DataKi: 0.0810nMAssay Description:Displacement of [3H]ZM241385 from human A2AAR expressed in HEK293 cells membrane assessed as inhibition constant preincubated for 5 mins followed by ...More data for this Ligand-Target Pair
Affinity DataKi: 0.302nMAssay Description:Displacement of [3H]ZM241385 from human A2AAR expressed in HEK293 cells membrane assessed as inhibition constant preincubated for 5 mins followed by ...More data for this Ligand-Target Pair
Affinity DataKi: 7.40nMAssay Description:Displacement of [3H]DPCPX from human A1AR expressed in HEK293 cells membrane assessed as inhibition constant preincubated for 5 mins followed by [3H]...More data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Displacement of [3H]DPCPX from human A1AR expressed in HEK293 cells membrane assessed as inhibition constant preincubated for 5 mins followed by [3H]...More data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Displacement of [3H]DPCPX from human A2BAR expressed in HEK293 cells membrane assessed as inhibition constant preincubated for 5 mins followed by [3H...More data for this Ligand-Target Pair
Affinity DataKi: 97nMAssay Description:Displacement of [3H]DPCPX from human A2BAR expressed in HEK293 cells membrane assessed as inhibition constant preincubated for 5 mins followed by [3H...More data for this Ligand-Target Pair
Affinity DataKi: 1.26E+3nMAssay Description:Displacement of [3H]HEMADO from human A3AR expressed in CHO-K1 cells membrane assessed as inhibition constant preincubated for 5 mins followed by [3H...More data for this Ligand-Target Pair
Affinity DataKi: 3.05E+3nMAssay Description:Displacement of [3H]HEMADO from human A3AR expressed in CHO-K1 cells membrane assessed as inhibition constant preincubated for 5 mins followed by [3H...More data for this Ligand-Target Pair
Affinity DataEC50: 119nMAssay Description:Antagonist activity at A2AAR in human T -cells assessed as increase in IL-2 production preincubated for 1 hr followed by CD3/CD28 monoclonal antibody...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Antagonist activity at A2AAR in human HEK293 cells assessed as inhibition of CGS21680-induced cAMP production preincubated for 15 mins followed by CG...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Antagonist activity at A2AAR in human HEK293 cells assessed as inhibition of CGS21680-induced cAMP production preincubated for 15 mins followed by CG...More data for this Ligand-Target Pair
Affinity DataEC50: 1.80nMAssay Description:Antagonist activity at A2AAR in human T -cells assessed as increase in IL-2 production preincubated for 1 hr followed by CD3/CD28 monoclonal antibody...More data for this Ligand-Target Pair