BDBM50613328 CHEMBL5280425

SMILES Cc1cn(-c2cccc(F)c2)c2ccc(cc12)C(=O)NS(C)(=O)=O

InChI Key InChIKey=DNBLZRUMMGYSLS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50613328   

TargetSodium channel subunit beta-2(Homo sapiens)TBA
LigandPNGBDBM50613328(CHEMBL5280425)
Affinity DataIC50:  38nMAssay Description:Inhibition of human Nav1.7/beta1/2 transfected in HEK293-A cells assessed as inhibition of channel current incubated for 5.5 mins by high-throughput ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50613328(CHEMBL5280425)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of human Nav1.5/beta1/2 transfected in HEK293-A cells assessed as inhibition of channel current incubated for 5.5 mins by high-throughput ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50613328(CHEMBL5280425)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of human Nav1.1/beta1/2 transfected in HEK293-A cells assessed as inhibition of channel current incubated for 5.5 mins by high-throughput ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetSodium channel subunit beta-2(Mus musculus)TBA
LigandPNGBDBM50613328(CHEMBL5280425)
Affinity DataIC50:  900nMAssay Description:Inhibition of mouse Nav1.7/beta1/2 transfected in HEK293-A cells assessed as inhibition of channel current incubated for 5.5 mins by high-throughput ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed