BDBM523008 1-(4-(4-amino-7- cyclopropyl-7H- pyrrolo[2,3- d]pyrimidin-5-yl)-2- fluorophenyl)-3-(3- (hydroxymethyl)isoxazol- 5-yl)urea::US11161852, Compound 36::US11713321, Example 36

SMILES Nc1ncnc2n(cc(-c3ccc(NC(=O)Nc4cc(CO)no4)c(F)c3)c12)C1CC1

InChI Key InChIKey=YNQDXFATSOILEK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 523008   

TargetSerine/threonine-protein kinase Nek7(Homo sapiens (Human))
Halia Therapeutics

US Patent
LigandPNGBDBM523008(1-(4-(4-amino-7- cyclopropyl-7H- pyrrolo[2,3- d]py...)
Affinity DataIC50:  1.00E+3nMAssay Description:Casein substrate (from bovine milk, hydrolyzed and partially dephosphorylated mixture of α, β and κ caseins, obtained from Sigma Aldri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Nek7(Homo sapiens (Human))
Halia Therapeutics

US Patent
LigandPNGBDBM523008(1-(4-(4-amino-7- cyclopropyl-7H- pyrrolo[2,3- d]py...)
Affinity DataIC50:  1.00E+3nMAssay Description:Casein substrate (from bovine milk, hydrolyzed and partially dephosphorylated mixture of α, β and a caseins, obtained from Sigma Aldrich, c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent